• glibenclamide In the belief that DNA based

  2020-10-31

  

  In the belief that DNA-based nanosensors and DNA microarrays should be easier to operate, faster, more accurate and more economically viable than PCR-based techniques, an electrochemical DNA biosensor was designed for detection of G. boninense[9], [10]. This was developed based on a gold electrode m

• We then evaluated in vivo DHODH mRNA

  2020-10-31

  

  We then evaluated in vivo DHODH mRNA amikacin sulfate using data from TCGA (Lee, Palm, Grimes, & Ji, 2015). To perform a pan-disease comparison of DHODH expression, log2 TPM expression values were converted to z-scores calculated per patient. Fig. 6 shows that across all 34 diseases (9726 unique pa

• Soybean Glycine max is an important oilseed and

  2020-10-31

  

  Soybean (Glycine max) is an important oilseed and can be a useful source of epoxy fatty acids (EFAs). This UFA contains an oxygen bridge across adjacent carbon atoms at single or multiple positions in the acyl chain, making them highly reactive and prone to cross-linking, and thus valuable industria

• br Materials and methods br

  2020-10-31

  

  Materials and methods Results Discussion Our previous investigation demonstrated that some genes in the latex that were involved in rubber biosynthesis were regulated by exogenous JA, and Hbvp1 is one of the JA-responsive genes in the latex of rubber trees [23]. In this study, the Hbvp1 enc

• SAG Proteolysis by CPs is crucially

  2020-10-31

  

  Proteolysis by CPs is crucially important for cereal seed development and germination. However, these enzymes must be tightly controlled. Pre-harvest sprouting is a phenomenon in which the control of CPs is disrupted. This disruption manifests in the premature synthesis and activation of CPs, leadin

• After repeated intermittent exposure to

  2020-10-31

  

  After repeated, intermittent exposure to a psychostimulant an augmentation of drug response to motor activity is commonly observed, a phenomenon known as behavioral sensitization (Kalivas and Stewart, 1991, Steketee and Kalivas, 2011). On the other hand, several reports have pointed out that stress

• ziprasidone hcl In summary our findings indicate that

  2020-10-31

  

  In summary, our findings indicate that bFGF stimulates CPT1 expression, FA oxidation and lactate production with the participation of PPARβ/δ activation. On the other hand, this investigation shows that FSH concomitantly regulates the expression of genes involved in FA metabolism and in mitochondria

• Materials and methods br Results br

  2020-10-31

  

  Materials and methods Results Discussion Microbial production of trans-4Hyp, an added-value amino nos inhibitor for pharmaceuticals, offers significant advantages over conventional chemical extraction in economic and environmental aspects. However the low titer and productivity with the exis

• Resistance to avermectins has been associated with point mut

  2020-10-31

  

  Resistance to avermectins has been associated with point mutations of GluCls in C. elegans, D. melanogaster, T. urticae and P. xylostella (Dent et al., 2000; Dermauw et al., 2012; Kane et al., 2000; Kwon et al., 2010; Wang et al., 2016a, 2017). Our electrophysiological study found a 8.2-fold reducti

• In this report we established

  2020-10-31

  

  In this report, we established mouse models suitable for human retinal cell transplantation by introducing phosphodiesterase 6B (Pde6b) mutant allele from retinal degeneration (rd) mouse models into NOG background. Pde6b (rd1) and Pde6b (rd10) mice are well-studied and frequently used animal models

• From an industrial perspective the low

  2020-10-31

  

  From an industrial perspective, the low turnover numbers and limited substrate scope of α-KG halogenases still represents a significant challenge. However, in light of the fact that currently no chemical processes are available for the selective halogenation of aliphatic carbon centers in complex mo

• Oligomycin A br Results and discussion br Conclusion

  2020-10-31

  

  Results and discussion Conclusion Based on the structure of ThDP, in this study, a series of novel ThDP analogs 6a-6g and 8a-8g were designed by optimizing triazole-benzene linker and modifying the substituent group of triazole ring. Then they were synthesized as potential inhibitors of Cy-PDH

• br Restenosis after angioplasty remains

  2020-10-31

  

  Restenosis after angioplasty remains a remarkable challenge, although drug-eluting stents have reduced the incidence of restenosis considerably . Vascular smooth muscle MK1775 (VSMCs) play a pivotal role in the development of intimal thickening and restenosis. VSMCs proliferate and migrate from t

• During these processes meiotic recombination plays a

  2020-10-31

  

  During these processes, meiotic recombination plays a critical role by physically associating homologs and ensures accurate chromosome segregation. In addition, meiotic recombination redistributes genetic material between homologs, resulting in haplotype diversity among progeny, impacting ecological

• Previous synthetic lethal screening efforts Cox et

  2020-10-31

  

  Previous synthetic lethal screening efforts (Cox et al., 2014) have mainly used RNAi as a means of identifying potential targets (Barbie et al., 2009, Kim et al., 2016, Luo et al., 2009, Scholl et al., 2009), although a few screens (Shaw et al., 2011, Steckel et al., 2012) have been performed with s

14442 records 754/963 page Previous Next First page 上5页 751752753754755 下5页 Last page