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Park et al expanded their own model
2021-02-11
Park et al. [34] expanded their own model as hydrogen- bonding lattice fluid EOS (NLF-HB) [35] for calculating the activity coefficients of aqueous amino 2-Deoxyadenosine 5-diphosphate solution. Further, Pazuki et al. [36] extended the perturbed hard chain theory which has been proposed by Beret an
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Previously we had proposed three possible models with one be
2021-02-11
Previously we had proposed three possible models, with one being that hCrm1 fundamentally interacted more favorably or strongly with Rev-RRE complex, compared to mCrm1. We decided to test that model, which was the simplest and most straightforward, by both biochemical and genetic means. By using bac
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The mechanisms in the central
2021-02-11
The mechanisms in the central nervous system (CNS) controlling the sympathetic tone of the olopatadine hydrochloride are associated to behavioral strategies, such as those involved in response to stress. In this regard, morphine withdrawal induces profound and severe stress reactions evidenced by en
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Introduction The carnitine choline acyltransferase
2021-02-11
Introduction The carnitine/choline acyltransferase family is a family of enzymes that play diverse roles, ranging from (the regulation of) SGI-1027 and fuel metabolism in mitochondria and peroxisomes to the generation of the neurotransmitter acetylcholine. In mammals, this family consists of seven
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Some studies have integrated the use of cloud computing
2021-02-11
Some studies have integrated the use of cloud computing with user interfaces in the domain of our proposal (i.e. UI). In [24] the authors work with Android devices to achieve more flexibility in the user interfaces by making use of information about the environment (for example, with an ambient ligh
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COMT expression protein level and activity are down regulate
2021-02-11
COMT expression, protein level and activity are down regulated by E2. Using estrogen receptor (ER) positive MCF-7 cells, Xie et al. demonstrated an E2 dose dependent (1, 10 and 100 nM) decrease in S-COMT 1.3 kb mRNA that was maximum after 48 h (Xie et al., 1999). A similar decrease was not observed
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It is now known that cholinergic signaling
2021-02-11
It is now known that cholinergic signaling plays a vital role in controlling many peripheral functions including skeletal and smooth muscle contraction, autonomic postganglionic neuron activation, parasympathetic end-organ activation (e.g., salivary, lacrimal and bronchial glands), regulation of car
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br Acknowledgements br Introduction Ischemic retinopathy is
2021-02-10
Acknowledgements Introduction Ischemic retinopathy is common to the major causes of blindness, including proliferative diabetic retinopathy, venous occlusion, and retinopathy of prematurity. The hypoxia that follows retinal capillary obliteration drives deregulated growth of new blood vessels
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Our finding that VEGF A induced downregulation
2021-02-10
Our finding that VEGF-A induced downregulation of EphB4 is VEGFR2 dependent (Fig. 4A) is not surprising because VEGFR2 is the primary signaling receptor of VEGF-A in EC [34]. However, our finding that VEGF-A induced upregulation of dll4 Pyridoxal isonicotinoyl hydrazone is not inhibited by VEGFR2 in
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br Discussion The etiology of
2021-02-10
Discussion The etiology of autoimmune diseases including psoriasis is intricate and a composite of environmental and biological factors. There are very limited studies available that report the association analysis of ACE I/D polymorphism with psoriasis risk. In the current study we report on as
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The quaternary structure of many of the family B members
2021-02-10
The quaternary structure of many of the family B members (i.e., secretin, glucagon, glucagon-like peptide and silibinin synthesis receptors) have been actively studied and it has been demonstrated that they can form homodimers/oligomers (Gao et al., 2009; Ng & Chow, 2015; Ng, Lee, & Chow, 2013). Ha
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br Protein acetylation Several reports show that
2021-02-10
Protein acetylation Several reports show that MTX is able to induce acetylation of histones and other proteins. Extensive studies have established that histone acetylation is primarily associated with gene activation. Acetylation occurs at lysine residues on the amino-terminal tail of the protein
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A number of immune relevant
2021-02-10
A number of immune-relevant genes have been studied to explore the immunologic mechanisms in large yellow croakers; however, the chemokine receptor CXCR family has never been studied in this organism. Chemokines are a large superfamily of chemotactic cytokines that are utilized to direct the traffic
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br Results br Discussion GPCRs recognize a
2021-02-10
Results Discussion GPCRs recognize a broad range of molecules with a vast chemical dna synthesis inhibitors through different mechanisms. Our understanding of the recognition of lipid mediators by GPCRs primarily comes from the structural studies of receptors for lysophospholipids and endocan
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When a hour delay period was implemented for the WRAM
2021-02-09
When a 6-hour delay mglur antagonist was implemented for the WRAM, neither of the E2-treated groups (E2-only and E2 + Levo) differed in WMC errors between the postdelay trials and the baseline trials. This suggests that exogenous E2 treatment protected from a delay-induced impairment in performance
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