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For some fishstocks landed by FMA ACE fishers
2024-11-13
For some fishstocks landed by FMA3 ACE fishers, the designated Quota Management Area (QMA) extends beyond the geographic demarcations of FMA3.Fig. 1 shows the ten FMAs, highlighting the study area FMA3. Gurnard 3 QMA is included as an example of a QMA that 99021 extends across more than one FMA. As
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Subsequently Palvimaki et al corroborated Ni and Miledi
2024-11-13
Subsequently, Palvimaki et al. (1999) corroborated Ni and Miledi's study by demonstrating that treatment with fluoxetine leads to 43% occupancy of the 5-HT2C receptors. Moreover, the affinity of fluoxetine for 5HT2C receptors (Ki 65 nM) is close to its affinity for 5-HT transporters (Ki 33 nM) (Ni a
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In an effort to determine if one ARI was more
2024-11-13
In an effort to determine if one 5ARI was more effective than the other, the Enlarged Prostate International Comparator Study (EPICS) [17] compared treatment with finasteride and dutasteride in 1630 men over the age of 50 and concluded that after one year of treatment, both groups had statistically
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Regarding brain tumors AXL has been implicated in gliomagene
2024-11-13
Regarding R 59-022 tumors, AXL has been implicated in gliomagenesis and chemoresistance [39]. Previous investigations found that AXL is constitutively phosphorylated in many glioma cell lines, murine xenograft tumors and primary patient tumor samples [40]. Immunohistochemical analysis of AXL and Ga
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br Increased blood ATX and LPA in liver
2024-11-13
Increased blood ATX and LPA in liver fibrosis Although previous in vitro findings have suggested a link between LPA and liver fibrosis in vivo, whether LPA plays a primary role in the pathogenesis of liver fibrosis has remained uncertain. No phenotypic changes in livers of LPA receptor-deficient
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tgf beta receptor br Materials and methods br Results br Dis
2024-11-12
Materials and methods Results Discussion I/R injury is characterized by myocardial damage triggered by the ischemic insult followed by reperfusion injury. While the primary insult depends mainly on the severity and duration of blood flow restriction and the breakdown of ATP-dependent tgf be
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Napabucasin br Introduction Humans have consumed mushrooms f
2024-11-12
Introduction Humans have consumed mushrooms for centuries because of their high nutrient content and low lipid content, as well as their excellent flavor and texture [1]. Edible mushrooms possess notable medicinal properties and bioactivities, including antitumor, antiviral, antidiabetic, and ant
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In order to further explore whether the cytoprotective
2024-11-12
In order to further explore whether the cytoprotective effect of isogarcinol against oxidative stress in H2O2-induced HepG2 CHS828 synthesis is a consequence of the breakdown of the endogenous antioxidant defence mechanism, we measured the LDH release, MDA levels, GSH levels and SOD activity. A larg
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Recent studies revealed that certain plant derived compounds
2024-11-12
Recent studies revealed that certain plant-derived compounds can also interfere with AR function. One way of such an interference is by modulating its expression levels. This is the case for the two flavonoids quercetin and luteolin that have been reported to repress the function of AR by inhibiting
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Our previous study showed that TRIM could
2024-11-12
Our previous study showed that TRIM31 could target TSC1-TSC2 complex and contributed to the clinical cancer progression [6]. In this study, we showed that TRIM31 could directly target p53 for ubiquitous degradation and further mediated anoikis-resistance of HCC cells. To further clarify the role of
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nm to lb receptor br Experimental Procedures br Acknowledgme
2024-11-12
Experimental Procedures Acknowledgments Introduction Cellular and molecular mechanisms underlying synaptic plasticity in the nm to lb receptor are thought to be involved in memory acquisition. Synaptic plasticity is categorised into two main types, long-term depression (LTD) and long-term
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br Concluding remarks Enhanced membrane binding
2024-11-12
Concluding remarks Enhanced membrane binding upon calcium stimulation in Diphenyleneiodonium chloride suggests a pre-requisite step that involves a conformational change in LOX. This might facilitate it to tether to the membrane and regulate enzyme activity. The calcium binding loops and the put
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PAN induced nephrosis was accompanied
2024-11-12
PAN-induced nephrosis was accompanied by loss of body weight, decrease of food intake, increase in urine volume and increases in triglycerides and cholesterol levels, which have been reported previously (Natori et al., 1996). Except for urine volume, each one of these measures was improved by A-3069
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br Experimental section br Conflicts of interest br Acknowle
2024-11-12
Experimental section Conflicts of interest Acknowledgments This work was partly supported by INSA-Rouen, Rouen University, CNRS, Labex SynOrg (ANR-11-LABX-0029), Région Haute-Normandie. Introduction A key component of the integrated management of key pests such as codling moth (Cydia po
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br Acknowledgments This work was supported
2024-11-12
Acknowledgments This work was supported by the R&D Program of the Institutional Research Program of KRICT (SI1701-02), and by the Next generation carbon upcycling project of Ministry of Science and ICT. JSC is kindly grateful to the National Research Council of Science and Technology (NST) for fi
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