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TC-I 2000 While TUNEL staining is traditionally thought to b
2022-06-13
While TUNEL staining is traditionally thought to be an apoptosis marker, studies have shown that TUNEL can stain necrotic TC-I 2000 [19], [20], [21]. Furthermore, DNA degradation has also been observed in necrotic cells [22]. TUNEL staining alone is therefore insufficient to distinguish apoptosis f
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br Conclusion br Ethics statements
2022-06-13
Conclusion Ethics statements file Conflict of interest Acknowledgements This study was supported by the National Research Foundation of Korea (NRF) Grant funded by the Korean Government (MSIP) (Nos. 2011-0030074 and 2018R1D1A3B07050361) and Sookmyung Women’s University Specialization Pro
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The current gold standard for diagnosing
2022-06-10
The current gold standard for diagnosing BAM or BAD is the measurement of BA turnover rate with radiolabelled tauroselcholic (75selenium) quercetine (also known as the SeHCAT retention test). SeHCAT test involves the use of a synthetic analogue of naturally occurring conjugated taurocholic acid and
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br Materials and methods br
2022-06-10
Materials and methods Results Discussion Several studies highlighted an improvement of glycaemic control in diabetic patients receiving sunitinib, while the underlying mechanism remained still elusive [3], [4], [5], [6], [8]. The present study gives evidence that sunitinib directly and spec
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Magtanong et al observed that caspase dependent
2022-06-10
Magtanong et al. (2019) observed that caspase-dependent apoptotic lipotoxicity of saturated fatty acids is suppressed by exogenous MUFAs. This may explain the ability of MUFAs to prevent atherosclerosis, in contrast to the pathogenicity of saturated fatty acids. Moreover, MUFAs may promote while PUF
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Therefore the histomorphology and the comprehensive analysis
2022-06-10
Therefore, the histomorphology and the comprehensive analysis of TMJ-RA pathogenesis need to be completed although clinical findings in TMJ-RA are similar to RA in other joints [41]. Especially for the dentist, the difficulties associated with diagnosing TMJ-RA patients [49] posing challenges to dia
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Enhancer of zeste homolog EZH which functions
2022-06-10
Enhancer of zeste homolog 2 (EZH2), which functions as a methyltransferase, is a critical subunit of polycomb repressive complex 2 (PRC2), which has been demonstrated to be involved in the development of the GANT61 australia [23]. Aberrant expression of EZH2 has been found to be associated with a v
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Figure shows the network of the persons with diagnosed
2022-06-10
Figure 2 shows the network of the 47 persons with diagnosed HIV and their 192 contacts. Of the contacts, 149 (78%) were first-generation contacts and 43 (22%) were second-generation contacts. Color and shape combinations used for network nodes (i.e., persons) allow one to simultaneously discern past
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Despite the increased risk for infections and
2022-06-10
Despite the increased risk for infections and the widespread availability of vaccines, reported vaccine coverage rates among HIV-infected adult patients are low [17], [18], [19], [20], [21]. Data from two studies in the United States suggested that influenza vaccination coverage among HIV-infected p
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The third group also included samples
2022-06-10
The third group also included samples belonging to subjects with undetectable viraemia, for which the negative or persistence of the indeterminate WB result in subsequent samples indicated a non-HIV infection. In this subgroup, the VITROS HIV Combo test (as well as the other two tests) was negative
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Ursodiol Not only does G a GLP complex appear to play
2022-06-10
Not only does G9a/GLP complex appear to play a role (albeit a seemingly conflicting one) in LTP maintenance, it may also be involved in long-term depression (LTD) (). At hippocampal CA1 synapses, LTD can be induced by pharmacological or synaptic stimulation of Group 1 metabotropic glutamate receptor
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br Results and Discussion The Set sequence is homologous
2022-06-10
Results and Discussion The Set7 sequence is homologous to the other identified histone methyltransferases in S. pombe (Figure S1) and also shares similarity with human HMTases, H3K9 GLP/Ga9, and H4K20 SUV420H1 (Figure S1). Set7 fused with the GFP (Set7-GFP) localized in the nucleus and cytoplasm
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We reveal that the four well known vertebrate families of
2022-06-10
We reveal that the four well known vertebrate families of KAT enzymes (GNAT, MYST, P300/CBP, Basal transcription factor/nuclear receptor co-activator) seem to be conserved (Karmodiya et al., 2014; Roth et al., 2001; Sheikh & Akhtar, 2018) in the mangrove rivulus, together with Camello, a potential n
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The neurotransmitter histamine plays a key role in the
2022-06-10
The neurotransmitter histamine plays a key role in the sleep-wake cycle and in learning and memory. Alterations in Latrunculin B histamine levels are closely connected with central nervous system dysfunction, and are thought to contribute to neurological disorders, including Alzheimer's disease and
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While published data around the functional significance
2022-06-10
While published data around the functional significance of GPR84 are quite sparse, details of signaling pathways initiated by the receptor are even more limited, including in recombinant systems. In recombinant cells, GPR84 activation reportedly leads to Gi pathway activation, resulting in pertussis
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