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The protein kinase CK mediated phosphorylation of
2024-05-29

The protein kinase CK2-mediated phosphorylation of HMGN1 was implicated to be involved in age-associated amnesia in rats [31]. It was shown that the decreased level of HMGN1 phosphorylation due to the down-regulation of CK2 activity could cause amnesia in aged rats, whereas the treatment with protei
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br Materials and met http www apexbt com media
2024-05-28

Materials and methods Results The values for body weight are shown in Fig. 1. Body weight was measured every day. The body weight of the young mice in the control (i.e. no-stress) group was not significantly different from that of the young mice in the stress group. However, the middle-aged mi
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MD was the recipient of the Intergroupe
2024-05-28

MD was the recipient of the Intergroupe Francophone de Cancérologie Thoracique (IFCT) Alain Depierre Grant in 2014. JP was the recipient of the ARISTOT (Association de Recherche, d’Information Scientifique et Thérapeutique en Oncologie Thoracique) grant in 2016. Conflicts of interest statement
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glutathione s-transferase In this study for the first instan
2024-05-28

In this study, for the first instant we report the characterization, production and in silico structural analysis of BADH1 gene in B. haloduranss SMBPL06 isolated from the salt pan. Moreover, the sequence analysis of betaine aldehyde dehydrogenase from B. haloduranss SMBPL06 displayed several base s
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Since the first studies of betaine aldehyde oxidation in
2024-05-28

Since the first studies of betaine aldehyde oxidation in rats [13], the participation of betaine in the detoxification of homocysteine has well described, considering the activity of other choline alfoscerate as betaine homocysteine methyltransferase and methionine synthase. But, there is a lack of
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br Conclusions br Introduction During numerous physiological
2024-05-28

Conclusions Introduction During numerous physiological processes, aldehydes are generated from a variety of endogenous and exogenous precursors including amino acids, carbohydrates, and lipids [1]. Most aldehydes are highly reactive and cytotoxic due to the strong electrophilic nature of the t
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A previous study showed that miR c is involved in
2024-05-28

A previous study showed that miR-200c is involved in glucose-mediated pathological processes (Zhang, Guan, & Jin, 2017). Glucose metabolism is critical for the growth and proliferation of both normal lgk974 and cancer cells, and reprogramming glucose metabolism now has been considered as a target o
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br The role of AMPK beyond energy homeostasis
2024-05-28

The role of AMPK beyond Microcystin-LR homeostasis: regulating metabolism AMPK plays a major role in glucose homeostasis by modulating glucose transport in peripheral tissues [20]. Skeletal muscle, one of the main peripheral tissues involved in glucose uptake and disposal, expresses glucose tran
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br Discussion Myopathic EMG changes are frequently detected
2024-05-28

Discussion Myopathic EMG changes are frequently detected in patients with MuSK MG, unlike in AChR MG patients [10]. However, these EMG changes are not always accompanied by myopathic histopathological findings. It has been shown that mitochondrial abnormalities seem to be more prominent in MuSK M
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br Acknowledgement This work was funded
2024-05-28

Acknowledgement This work was funded by NIH/NINDS grant number NS080967 to C. Waites. Introduction Macro-autophagy also called autophagy is a conserved pathway for the lysosomal degradation and recycling of intracellular materials. It is instrumental for the homeostasis of cells and tissues a
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ryanodine br Conclusion GroEL from RA CH was
2024-05-28

Conclusion GroEL from RA-CH-1 was expressed and purified. The recombinant RaGroEL protein exhibited ATPase activity, which cooperated with GroES in ATP hydrolysis. Furthermore, the expression pattern of groEL revealed that groEL was up-regulated during stress response. Further studies are warrant
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Amphotericin B br Experimental section br Acknowledgements b
2024-05-28

Experimental section Acknowledgements Introduction DJ-1 is a highly conserved, homodimeric protein that was originally cloned as an oncogene capable of transforming Amphotericin B in cooperation with activated ras[1]. DJ-1 is over-expressed in multiple tumor types and is positively correlat
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Recently dairy proteins obtained from whey have received con
2024-05-27

Recently, dairy proteins obtained from whey have received considerable attention for their antioxidant bioactivity (Bayram et al., 2008; Haraguchi et al., 2011; Zhang et al., 2012). Bovine whey proteins (WP) are widely used in various foods for their nutritional, health-promoting, and functional va
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Protein microarrays represent just one of a
2024-05-27

Protein microarrays represent just one of a variety of experimental approaches that can be used to generate datasets of relevance to pathway mapping. Other approaches include protein NVP-BKM120 Hydrochloride receptor profiling techniques, such as antibody arrays [29], tissue arrays [30] and 2-dimen
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br Summary br Introduction With readily synthetic methods an
2024-05-27

Summary Introduction With readily synthetic methods and excellent chemical/physical characteristics, coumarins have received extensive attention and show great practical values in many fields, such as medicine discovery, dye chemistry, materials chemistry and so on [[1], [2], [3]]. Actually, o
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